2-(3,5-Dichlorophenoxy)-2,2-difluoroacetic acid CAS 1153780-39-2
| CAS No. | 1153780-39-2 |
| Molecular Formula | C8H4Cl2F2O3 |
| Molecular Weight | 257.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3,5-Dichlorophenoxy)-2,2-difluoroacetic acid (CAS 1153780-39-2), molecular formula C8H4Cl2F2O3 and molecular weight 257.02 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(3,5-Dichlorophenoxy)-2,2-difluoroacetic acid (C8H4Cl2F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 257.02 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(3,5-Dichlorophenoxy)-2,2-difluoroacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4Cl2F2O3 |
| Molecular Weight | 257.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
Related Dichlorophenoxy Standards
- 5-(3,5-Dichlorophenoxy)furan-2-carbaldehyde (CAS 1291489-06-9)
- 5-(2,3-Dichlorophenoxy)furan-2-carbaldehyde (CAS 1291489-24-1)
- 5-(3,4-Dichlorophenoxy)furan-2-carbaldehyde (CAS 1291490-42-0)
- 5-(2,5-Dichlorophenoxy)furan-2-carbaldehyde (CAS 1291492-48-2)
- 5-(1-(2,4-Dichlorophenoxy)ethyl)-1H-pyrazole (CAS 321998-97-4)
- 4-(3,5-dichlorophenoxy)pyrimidin-2-amine (CAS 1503974-35-3)
- 1-((3,4-Dichlorophenoxy)methyl)-1H-pyrazol-4-amine (CAS 1006315-93-0)
- 1-((2,5-Dichlorophenoxy)methyl)-1h-pyrazol-4-amine (CAS 1006437-13-3)
Recommended Standards
- 2-Bromo-1-fluoro-4-(2,2,2-trifluoroethyl)benzene (CAS 1099598-18-1)
- 1-Bromo-4-fluoro-2-(2,2,2-trifluoroethyl)benzene (CAS 1186194-80-8)
- 5-Bromo-6-(trifluoromethyl)pyrimidin-4-hydrazine, 97% (CAS 785777-95-9)
- 2-Bromo-4-fluoro-1-(2,2,2-trifluoroethyl)-benzene (CAS 1186194-81-9)
- 143130-93-2 2-(2-((6-(2-Cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-2-oxoacetic Acid Methyl Ester (CAS 143130-93-2)
- 914381-27-4 N-(3-Fluorophenethyl)dodecanamide N-[2-(3-Fluorophenyl)ethyl]dodecanamide (CAS 914381-27-4)
- 1-(5-(Trifluoromethyl)thiazol-4-yl)ethanone (CAS 900530-70-3)
- 2-(Pyrimidin-4-ylamino)acetic acid (CAS 72971-95-0)
- 2,3-Dihydrospiro[indene-1,3'-pyrrolidine]-5,6-diol (CAS 100038-04-8)
- 1-Ethoxy-2-methyl-2-propanamine hydrochloride (CAS 1231730-24-7)
- Benzyl 3-((2-chloro-N-isopropylacetamido)methyl)piperidine-1-carboxylate (CAS 1353980-81-0)
- 2-(4-Chlorophenyl)-N-(2-(p-tolylthio)ethyl)acetamide (CAS 477885-99-7)
- 2-[2-(2-Ethylphenoxy)ethyl]piperidinehydrochloride (CAS 1219949-29-7)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
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