4-[(cyclopropylmethyl)carbamoyl]benzoic acid CAS 1154359-47-3
| CAS No. | 1154359-47-3 |
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[(cyclopropylmethyl)carbamoyl]benzoic acid is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-[(cyclopropylmethyl)carbamoyl]benzoic acid (CAS 1154359-47-3), molecular formula C12H13NO3 and molecular weight 219.24 g/mol, is a CATO reference standard with documented purity and traceability.
4-[(cyclopropylmethyl)carbamoyl]benzoic acid (C12H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[(cyclopropylmethyl)carbamoyl]benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
Related cyclopropylmethyl Standards
- 3-[(cyclopropylmethyl)carbamoyl]benzoic acid (CAS 1154359-44-0)
- 4-(Cyclopropylmethyl)-2-methyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid (CAS 1708428-03-8)
- Methyl 4-(((cyclopropylmethyl)amino)methyl)benzoate (CAS 1019561-77-3)
- Ethyl 4-[(cyclopropylmethyl)amino]benzoate (CAS 1156280-40-8)
- 4-(((Cyclopropylmethyl)(methyl)amino)methyl)benzoic acid (CAS 1183278-69-4)
- 2-(Cyclopropylmethyl)-4-hydroxy-N,N-dimethylbenzamide (CAS 1243286-47-6)
- 2-(Cyclopropylmethyl)-5-hydroxy-N,N-dimethylbenzamide (CAS 1243390-78-4)
- 2-(Cyclopropylmethyl)-6-hydroxy-N,N-dimethylbenzamide (CAS 1243408-35-6)
Recommended Standards
- 2-(6-Amino-2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide (CAS 1154397-88-2)
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- 3-(Hydroxymethyl)-6-methoxy-1-methylquinolin-2(1H)-one (CAS 114561-28-3)
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