3-Chloro-6-(2,6-difluorophenyl)pyridazine CAS 1154600-74-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1154600-74-4
Molecular FormulaC10H5ClF2N2
Molecular Weight226.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Chloro-6-(2,6-difluorophenyl)pyridazine CAS 1154600-74-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 226.61 g/mol gives 3-Chloro-6-(2,6-difluorophenyl)pyridazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-Chloro-6-(2,6-difluorophenyl)pyridazine (CAS 1154600-74-4) is a high-purity analytical reference standard with the molecular formula C10H5ClF2N2 and a molecular weight of 226.61 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 3-Chloro-6-(2,6-difluorophenyl)pyridazine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 226.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H5ClF2N2
Molecular Weight226.61 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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