1-(4-Amino-2-fluorophenyl)-N,N-dimethylpiperidin-4-amine CAS 1154665-52-7

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Amino-2-fluorophenyl)-N,N-dimethylpiperidin-4-amine.

1-(4-Amino-2-fluorophenyl)-N,N-dimethylpiperidin-4-amine (CAS 1154665-52-7) is a high-purity analytical reference standard with the molecular formula C13H20FN3 and a molecular weight of 237.32 g/mol.

Structurally, 1-(4-Amino-2-fluorophenyl)-N,N-dimethylpiperidin-4-amine (C13H20FN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 237.32 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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