5-Chloro-3,4-dihydro-2h-1-benzopyran-3-one CAS 1154740-80-3
| CAS No. | 1154740-80-3 |
| Molecular Formula | C9H7ClO2 |
| Molecular Weight | 182.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-3,4-dihydro-2h-1-benzopyran-3-one (CAS 1154740-80-3), molecular formula C9H7ClO2 and molecular weight 182.60 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 5-Chloro-3,4-dihydro-2h-1-benzopyran-3-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-3,4-dihydro-2h-1-benzopyran-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7ClO2 |
| Molecular Weight | 182.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 5-Chloro-7-methylisobenzofuran-1(3H)-one (CAS 118343-26-3)
- 7-Chloro-5-hydroxy-2,3-dihydro-1H-inden-1-one (CAS 1199782-69-8)
- 5-Chloro-2,3-dihydrochromen-4-one (CAS 1199782-82-5)
- 4-Chloro-6-hydroxy-2,3-dihydro-1H-inden-1-one (CAS 1199782-98-3)
- 5-Chloro-6-hydroxy-2,3-dihydro-1H-inden-1-one (CAS 1228678-18-9)
- 6-Chloro-5-hydroxy-2,3-dihydro-1H-inden-1-one (CAS 1260012-31-4)
- 2-Chloro-4-ethenylbenzoic acid (CAS 1266121-77-0)
- 5-Chloro-2-vinylbenzoic acid (CAS 1467773-21-2)
Recommended Standards
- 4-chlorobicyclo[4.2.0]octa-1(6),2,4-triene-7-carboxylic acid (CAS 1135492-13-5)
- (6-Chlorobenzofuran-2-yl)methanol (CAS 1089682-04-1)
- 1-(4-Chlorophenyl)propane-1,2-dione (CAS 10557-21-8)
- (1,2,4-Oxadiazol-3-yl)methanesulfonyl chloride (CAS 1596005-08-1)
- 7-Chloro-N-(2-(dimethylamino)ethyl)benzo[c][1,2,5]oxadiazole-4-sulfonamide (CAS 664985-43-7)
- TRimethyl[(2-methylferrocenyl)methyl]ammonium iodide (CAS 12111-93-2)
- 3-(((Benzyloxy)carbonyl)amino)-3-(2-chlorophenyl)propanoic acid (CAS 773867-64-4)
- (3S)-3-Amino-N-cyclopropyl-2-hydroxyheptanamidehydrochloride(1:1) (CAS 1137141-25-3)
- Tert-butyl (3,3,4,4,5,5,6,6,6-nonafluorohexyl) carbonate (CAS 1980085-06-0)
- 7-Bromo-2,6-dichloroquinazolin-4-amine (CAS 2384855-93-8)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with 2-hydroxyethyl 2-propenoate and 2-propenoic acid (CAS 66747-40-8)
- (S)-(-)-Canadine Di-p-toluoyl-D-tartrate (CAS 61065-22-3)
- 2-((1-(Furan-2-ylmethyl)-5-phenyl-1H-imidazol-2-yl)thio)-1-(pyrrolidin-1-yl)ethan-1-one (CAS 1207007-18-8)
- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com