2-(7-Fluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 1154741-03-3
| CAS No. | 1154741-03-3 |
| Molecular Formula | C15H20BFO3 |
| Molecular Weight | 278.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(7-Fluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C15H20BFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(7-Fluorochroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1154741-03-3), molecular formula C15H20BFO3 and molecular weight 278.13 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H20BFO3 |
| Molecular Weight | 278.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Fluorochroman Standards
- (6-Fluorochroman-2-yl)(piperidin-1-yl)methanone (CAS 878208-57-2)
- Methyl 6-Fluorochroman-2-carboxylate (CAS 874649-82-8)
- (R)-6-Fluorochroman-2-carboxylic acid (CAS 129101-37-7)
- 6-Fluorochroman-2-carboxylic acid (CAS 99199-60-7)
- (7-Fluorochroman-2-yl)methanol (CAS 1193393-01-9)
- (6-Fluorochroman-8-yl)methanol (CAS 1196147-64-4)
- (6-Fluorochroman-3-yl)methanol (CAS 1694582-32-5)
- (7-Fluorochroman-3-yl)methanol (CAS 1823364-10-8)
Recommended Standards
- 6-Chloro-3-(4-chlorophenyl)-2H-1,4-benzoxazine (CAS 112030-47-4)
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- 2-Hydroxy-4-methoxy-N-(1-methyl-1h-pyrazol-3-yl)benzamide (CAS 1133718-01-0)
- 1-(1H-imidazol-2-yl)piperazine dihydrochloride (CAS 1795503-50-2)
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