N-(2,5-difluorophenyl)tetrahydro-2H-pyran-4-amine CAS 1154889-33-4
| CAS No. | 1154889-33-4 |
| Molecular Formula | C11H13F2NO |
| Molecular Weight | 213.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(2,5-difluorophenyl)tetrahydro-2H-pyran-4-amine (C11H13F2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies N-(2,5-difluorophenyl)tetrahydro-2H-pyran-4-amine (CAS 1154889-33-4), a certified reference material (molecular formula C11H13F2NO, MW 213.22 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(2,5-difluorophenyl)tetrahydro-2H-pyran-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13F2NO |
| Molecular Weight | 213.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 1-[(2,4-Difluorophenyl)methyl]pyrrolidin-3-ol (CAS 1033012-65-5)
- N-(3,4-difluorophenyl)tetrahydro-2H-pyran-4-amine (CAS 1157008-32-6)
- n-(3,5-Difluorophenyl)tetrahydro-2h-pyran-4-amine (CAS 1157009-62-5)
- N-(2,4-difluorophenyl)pivalamide (CAS 124704-01-4)
- 4-(2,4-Difluorophenyl)piperidin-4-ol (CAS 1274933-78-6)
- 4-(2,6-Difluorophenyl)piperidin-4-ol (CAS 1274933-84-4)
- 4-(2,4-Difluorophenyl)tetrahydro-2H-pyran-4-amine (CAS 1343080-01-2)
- 4-(3,4-Difluorophenyl)tetrahydro-2H-pyran-4-amine (CAS 1343262-94-1)
Recommended Standards
- N-(cyclopropylmethyl)-3-(difluoromethoxy)aniline (CAS 1153340-22-7)
- N-(cyclopropylmethyl)-4-(difluoromethoxy)aniline (CAS 1156168-85-2)
- 4-(2,3-Difluorophenoxy)piperidine (CAS 1062241-40-0)
- (1-(4-(Difluoromethoxy)phenyl)cyclopropyl)methanamine (CAS 1037131-62-6)
- (3-Isopropylphenyl)trimethylsilane (CAS 18027-96-8)
- 2-Chloro-4-(difluoromethyl)-6-fluoropyridine-3-sulfonamide (CAS 1804669-87-1)
- (S)-Methyl pyrrolidine-3-carboxylate 2,2,2-trifluoroacetate (CAS 1523530-27-9)
- N-Allylbenzylamine (CAS 4383-22-6)
- (3,3-Difluorotetrahydro-2H-pyran-4-yl)methanol (CAS 1782291-14-8)
- 2-Chloro-4-(2-fluorophenyl)pyrimidine (CAS 1227570-74-2)
- 2-Formyl Loratadine (CAS 1076198-15-6)
- GlcNPhth[36Bn,4Ac]-β-MP (CAS 140615-77-6)
- 6-(Azetidin-1-yl)nicotinic acid (CAS 1334486-29-1)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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