1-(2-Chloro-6-fluorophenyl)ethane-1,2-diamine CAS 1154940-72-3

Description

The occurrence of 1-(2-Chloro-6-fluorophenyl)ethane-1,2-diamine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(2-Chloro-6-fluorophenyl)ethane-1,2-diamine (CAS 1154940-72-3), molecular formula C8H10ClFN2 and molecular weight 188.63 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(2-Chloro-6-fluorophenyl)ethane-1,2-diamine (C8H10ClFN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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