1-(5-Chloro-2-fluorophenyl)-1h-pyrazole-3-carboxylic acid CAS 1155049-47-0
| CAS No. | 1155049-47-0 |
| Molecular Formula | C10H6ClFN2O2 |
| Molecular Weight | 240.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(5-Chloro-2-fluorophenyl)-1h-pyrazole-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(5-Chloro-2-fluorophenyl)-1h-pyrazole-3-carboxylic acid (CAS 1155049-47-0), a certified reference material (molecular formula C10H6ClFN2O2, MW 240.62 g/mol) for analytical method development and quality control.
The molecular framework of 1-(5-Chloro-2-fluorophenyl)-1h-pyrazole-3-carboxylic acid (C10H6ClFN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(5-Chloro-2-fluorophenyl)-1h-pyrazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6ClFN2O2 |
| Molecular Weight | 240.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-(2-Chloro-4-fluorophenyl)-1h-pyrazole-3-carboxylic acid (CAS 1152535-69-7)
- 1-(3-Chloro-2-fluorophenyl)-1h-pyrazole-3-carboxylic acid (CAS 1152537-34-2)
- 3-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carboxylic acid (CAS 1152540-21-0)
- 2-Chloro-6-fluoro-3-methoxyquinoxaline-5-carbaldehyde (CAS 1221280-94-9)
- 5-Chloro-1-(2-fluorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 1355181-07-5)
- 6-(2-Chloro-4-fluorophenyl)pyrimidine-2,4(1H,3H)-dione (CAS 1467448-54-9)
- 2-Chloro-6-fluoroquinazoline-4-acetic Acid (CAS 1784510-27-5)
- 2-Chloro-8-fluoroquinazoline-4-acetic Acid (CAS 1784613-17-7)
Recommended Standards
- 5-(4-Chloro-3-fluorophenyl)-2-furoic Acid (CAS 893734-58-2)
- 4-Amino-7-chloro-6-fluorocinnoline-3-carboxamide (CAS 159831-72-8)
- 5-(3-Chloro-4-fluorophenyl)furan-2-carboxylic acid (CAS 496044-15-6)
- 1-(5-Chloro-2-methoxyphenyl)-2,2,2-trifluoroethan-1-ol (CAS 923170-54-1)
- Methyl 2-hydroxybut-3-enoate (CAS 5837-73-0)
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- (S)-3-Amino-3-(3,5-difluorophenyl)propanoic acid (CAS 1241679-50-4)
- Methyl 2-ethoxy-4-nitrobenzoate (CAS 24091-87-0)
- (2-Bromophenyl)(4-propylphenyl)methanol (CAS 1284417-86-2)
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- N-cyclopentyl-5-(1-tosylpyrrolidin-2-yl)pyridin-2-amine (CAS 1352532-27-4)
- 5-Oxo-5-(4-trifluoromethylphenyl)valeric acid (CAS 88699-88-1)
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