Ethyl 5-(chlorosulfonyl)thiophene-3-carboxylate CAS 1155084-57-3
| CAS No. | 1155084-57-3 |
| Molecular Formula | C7H7ClO4S2 |
| Molecular Weight | 254.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 5-(chlorosulfonyl)thiophene-3-carboxylate (CAS 1155084-57-3) is a high-purity analytical reference standard with the molecular formula C7H7ClO4S2 and a molecular weight of 254.71 g/mol.
Ethyl 5-(chlorosulfonyl)thiophene-3-carboxylate (C7H7ClO4S2) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 5-(chlorosulfonyl)thiophene-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7ClO4S2 |
| Molecular Weight | 254.71 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
Related Ethyl Standards
- methyl 3-(chlorosulfonyl)-4-methylthiophene-2-carboxylate (CAS 190375-00-9)
- Methyl 2-[5-(chlorosulfonyl)thiophen-2-yl]acetate (CAS 933730-54-2)
- Methyl 5-(chlorosulfonyl)-2-methylthiophene-3-carboxylate (CAS 2090072-28-7)
- Methyl 5-(chlorosulfonyl)-4-methylthiophene-2-carboxylate (CAS 423768-46-1)
- methyl 1-[(chlorosulfonyl)methyl]cyclohexane-1-carboxylate (CAS 374931-27-8)
- ethyl 4-(chlorosulfonyl)piperidine-1-carboxylate (CAS 1211538-59-8)
- ethyl 6-(chlorosulfonyl)pyridine-3-carboxylate (CAS 1249304-48-0)
- Ethyl 1-(chlorosulfonyl)piperidine-3-carboxylate (CAS 765962-70-7)
Recommended Standards
- 1-[(6-Chloropyridin-3-yl)methyl]piperidine-3-carboxylic acid (CAS 1119499-71-6)
- Ethyl 3-[(2-aminophenyl)imino]-2-chlorobutanoate (CAS 115525-73-0)
- 1-((7-Chlorobenzo[d][1,3]dioxol-5-yl)methyl)piperazine (CAS 1094558-26-5)
- 3-(2-Chlorophenyl)-1-cyclopropyl-1-(2-hydroxyethyl)urea (CAS 1155559-92-4)
- 6-Bromo-2-methoxy-3-methylpyridine (CAS 1256804-41-7)
- 1-(Bis(2-chloroethyl)amino)-3-(naphthalen-1-yloxy)propan-2-ol (CAS 73631-12-6)
- N,N-Bis(2-hydroxyethyl) Tridecylamine (CAS 18312-57-7)
- (4-((Diethylamino)methyl)-3-fluorophenyl)boronic acid (CAS 1333121-78-0)
- 3-Aminoquinoline (CAS 580-17-6)
- 4-Methylbicyclo[2.2.2]Octan-1-amine (CAS 1123-38-2)
- 6-(3,4,5-Trifluorophenoxy)hexanenitrile (CAS 1443354-23-1)
- 1-(6-(Dipropylamino)-5-methylpyridin-3-yl)propan-1-one (CAS 1355217-41-2)
- 3-Hydroxyanthranilic Acid-d3 (CAS 1794970-56-1)
- Semaglutide impurity 270 (CAS CATO-C4X-2226270)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com