4-Methyl-5-[(4-methylphenyl)methyl]-1,3-thiazol-2-amine CAS 1155997-55-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1155997-55-9
Molecular FormulaC12H14N2S
Molecular Weight218.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Methyl-5-[(4-methylphenyl)methyl]-1,3-thiazol-2-amine CAS 1155997-55-9 chemical structure

Description

The molecular framework of 4-Methyl-5-[(4-methylphenyl)methyl]-1,3-thiazol-2-amine (C12H14N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

4-Methyl-5-[(4-methylphenyl)methyl]-1,3-thiazol-2-amine (CAS 1155997-55-9) is a high-purity analytical reference standard with the molecular formula C12H14N2S and a molecular weight of 218.32 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Methyl-5-[(4-methylphenyl)methyl]-1,3-thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H14N2S
Molecular Weight218.32 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Nitrogen Atoms2
Sulfur Atoms1

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