5-Chloro-7-(trifluoromethyl)indoline CAS 1156231-67-2
| CAS No. | 1156231-67-2 |
| Molecular Formula | C9H7ClF3N |
| Molecular Weight | 221.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-7-(trifluoromethyl)indoline (C9H7ClF3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-Chloro-7-(trifluoromethyl)indoline (CAS 1156231-67-2), molecular formula C9H7ClF3N and molecular weight 221.61 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-7-(trifluoromethyl)indoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7ClF3N |
| Molecular Weight | 221.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 7-Chloro-4-(trifluoromethyl)indoline (CAS 1153392-34-7)
- 2-Chloro-6-cyclopropyl-4-(trifluoromethyl)pyridine (CAS 1251910-15-2)
- 1-{6-chloro-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-1H-1,2,4-triazole (CAS 1554112-95-6)
- 7-Chloro-2-(difluoromethyl)thiazolo[5,4-d]pyrimidine (CAS 1624606-96-7)
- 2-chloro-4-[1-(trifluoromethyl)cyclopropyl]pyridine (CAS 1803561-59-2)
- 2-chloro-5-[1-(trifluoromethyl)cyclopropyl]pyridine (CAS 1803611-16-6)
- 5-Chloro-6-(trifluoromethyl)isoindoline (CAS 2688734-91-8)
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Recommended Standards
- 8-Chlorotetrazolo[1,5-c]quinazolin-5(6H)-one (CAS 54013-08-0)
- (6-Amino-3-chloro-2-fluorophenyl)dimethylphosphine oxide (CAS 2638535-81-4)
- 7-Chlorotetrazolo[1,5-a]quinoxalin-4(5H)-one (CAS 161154-16-1)
- 8-Chloro-6-cyanoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1221792-13-7)
- 3-{[(tert-Butoxy)carbonyl](methyl)amino}cyclobutane-1-carboxylic acid (CAS 1234176-74-9)
- N-(pyridin-2-yl)pyridine-2-carbothioamide (CAS 39122-38-8)
- 4-Azetidinomethyl-3,5-dimethylbenzophenone (CAS 898756-71-3)
- [(4-Bromophenyl)methyl](butyl)amine (CAS 60509-40-2)
- 1217822-46-2 1323AD C15H21NO4 Methyl (2S,4S)-4-[4-(2-methoxyethyl)phenoxy]-2-pyrrolidinecarboxylate (CAS 1217822-46-2)
- 4-Bromo-2-(p-tolyl)pyridine (CAS 916824-56-1)
- 3-((1H-pyrazol-1-yl)methyl)benzoic acid (CAS 562803-68-3)
- Methyl 3-amino-6-fluoropicolinate (CAS 1804145-75-2)
- 2-bromo-6-phenylpyridin-3-amine (CAS 898568-39-3)
- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
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