1-[1-(3-bromophenyl)-5-methyl-1h-1,2,3-triazol-4-yl]ethan-1-one CAS 1157061-37-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1157061-37-4
Molecular FormulaC11H10BrN3O
Molecular Weight280.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-[1-(3-bromophenyl)-5-methyl-1h-1,2,3-triazol-4-yl]ethan-1-one CAS 1157061-37-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

1-[1-(3-bromophenyl)-5-methyl-1h-1,2,3-triazol-4-yl]ethan-1-one (CAS 1157061-37-4), molecular formula C11H10BrN3O and molecular weight 280.12 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-[1-(3-bromophenyl)-5-methyl-1h-1,2,3-triazol-4-yl]ethan-1-one (C11H10BrN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

As a certified reference material (CRM), 1-[1-(3-bromophenyl)-5-methyl-1h-1,2,3-triazol-4-yl]ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H10BrN3O
Molecular Weight280.12 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentBr-containing
Nitrogen Atoms3

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Why CATO?