1-(4-Chlorophenyl)-2-((2-hydroxyethyl)thio)ethan-1-one CAS 1157217-46-3
| CAS No. | 1157217-46-3 |
| Molecular Formula | C10H11ClO2S |
| Molecular Weight | 230.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(4-Chlorophenyl)-2-((2-hydroxyethyl)thio)ethan-1-one (CAS 1157217-46-3) is a high-purity analytical reference standard with the molecular formula C10H11ClO2S and a molecular weight of 230.71 g/mol.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 1-(4-Chlorophenyl)-2-((2-hydroxyethyl)thio)ethan-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 230.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO2S |
| Molecular Weight | 230.71 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 2-((4-Chlorophenyl)thio)propanehydrazide (CAS 1024477-91-5)
- Ethyl 2-((2-chlorophenyl)thio)acetate (CAS 137583-58-5)
- Ethyl 2-((3-chlorophenyl)thio)acetate (CAS 141819-39-8)
- 1-((2-Chlorophenyl)thio)-3-methoxypropan-2-one (CAS 1515012-94-8)
- 1-((3-Chlorophenyl)thio)-3-methoxypropan-2-one (CAS 1537391-78-8)
- 3-((4-Chlorophenyl)thio)butanoic acid (CAS 90919-34-9)
- 4-[(4-Chlorophenyl)thio]butanoic acid (CAS 29193-63-3)
- Ethyl 2-((4-chlorophenyl)thio)acetate (CAS 52377-68-1)
Recommended Standards
- 1,2,3,4-Tetrahydronaphthalene-2-sulfonyl chloride (CAS 102653-21-4)
- 2-(4-Ethylphenyl)ethene-1-sulfonyl chloride (CAS 1158094-54-2)
- 1-(3-Chloro-4-methoxyphenyl)-2-(methylthio)ethan-1-one (CAS 1179606-58-6)
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- n-(2-Chlorobenzyl)-1-methylpyrrolidin-3-amine (CAS 1248992-55-3)
- 1-(1-Ethyl-1h-pyrazol-4-yl)-2-morpholinoethan-1-one (CAS 1169973-74-3)
- 2-(1-Aminocyclopentyl)-6-methylpyrimidin-4(3H)-one (CAS 1283435-65-3)
- Methyl 2,5-dimethylbenzoate (CAS 13730-55-7)
- 2-Hydroxy-6,6-dimethylspiro[3.5]nonan-7-one (CAS 2758305-11-0)
- 4-Methyl-2-vinylthiophene (CAS 84548-65-2)
- Norfloxacin EP Impurity F HCl (CAS 67681-84-9(Free Base))
- 2-Chloro-5-(2-methoxyethoxy)phenylboronic acid (CAS 2096339-83-0)
- [(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]amine (CAS 90564-77-5)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
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