1-(2-Chlorophenyl)-2-(ethylthio)ethan-1-one CAS 1157221-81-2

Description

The occurrence of 1-(2-Chlorophenyl)-2-(ethylthio)ethan-1-one is closely related to sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(2-Chlorophenyl)-2-(ethylthio)ethan-1-one (CAS 1157221-81-2), molecular formula C10H11ClOS and molecular weight 214.71 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(2-Chlorophenyl)-2-(ethylthio)ethan-1-one (C10H11ClOS) is characterized by sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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