2-{[(2H-indazol-6-yl)amino]methyl}phenol CAS 1157521-96-4

Description

The occurrence of 2-{[(2H-indazol-6-yl)amino]methyl}phenol is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-{[(2H-indazol-6-yl)amino]methyl}phenol (CAS 1157521-96-4), molecular formula C14H13N3O and molecular weight 239.27 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-{[(2H-indazol-6-yl)amino]methyl}phenol (C14H13N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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