5-Bromo-8-methyl-1,2,3,4-tetrahydroquinoline CAS 1157721-71-5
| CAS No. | 1157721-71-5 |
| Molecular Formula | C10H12BrN |
| Molecular Weight | 226.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Bromo-8-methyl-1,2,3,4-tetrahydroquinoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Bromo-8-methyl-1,2,3,4-tetrahydroquinoline (CAS 1157721-71-5) is a high-purity analytical reference standard with the molecular formula C10H12BrN and a molecular weight of 226.11 g/mol.
Structurally, 5-Bromo-8-methyl-1,2,3,4-tetrahydroquinoline (C10H12BrN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 226.11 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Bromo-8-methyl-1,2,3,4-tetrahydroquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12BrN |
| Molecular Weight | 226.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 8-Bromo-3-methyl-1,2,3,4-tetrahydroquinoline (CAS 1017139-11-5)
- 6-Bromo-3-methyl-1,2,3,4-tetrahydroquinoline (CAS 1017336-71-8)
- 7-Bromo-8-methyl-1,2,3,4-tetrahydroquinoline (CAS 1155264-51-9)
- 2-Bromo-N-(cyclopropylmethyl)aniline (CAS 1156164-31-6)
- 5-Bromo-1-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 1176414-91-7)
- 7-Bromo-1-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 1176414-95-1)
- (6-Bromo-2,3-dihydro-1H-inden-1-yl)methanamine (CAS 1188142-10-0)
- (5-Bromo-2,3-dihydro-1H-inden-1-yl)methanamine (CAS 1188164-61-5)
Recommended Standards
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- TAT-cyclo-CLLFVY (CAS 1446322-66-2)
- Ethyl 2-(3,4-Dichlorophenyl)-5-methyloxazole-4-carboxylate (CAS 1443981-03-0)
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