5-Bromo-4-chloro-6-methoxypyrimidin-2-amine CAS 1158074-71-5
| CAS No. | 1158074-71-5 |
| Molecular Formula | C5H5BrClN3O |
| Molecular Weight | 238.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Bromo-4-chloro-6-methoxypyrimidin-2-amine (C5H5BrClN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 5-Bromo-4-chloro-6-methoxypyrimidin-2-amine (CAS 1158074-71-5), a certified reference material (molecular formula C5H5BrClN3O, MW 238.47 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5BrClN3O |
| Molecular Weight | 238.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 4-Bromo-5-chloro-N-methylfuran-2-carboxamide (CAS 1427021-10-0)
- Methyl 4-Bromo-5-chloro-1H-pyrrole-2-carboxylate (CAS 1629633-64-2)
- Methyl 4-Bromo-3-chloropyrrole-2-carboxylate (CAS 1629633-72-2)
- 5-Bromo-6-chloro-2-(methylamino)pyrimidin-4(3H)-one (CAS 1706429-53-9)
- 4-Bromo-3-chloro-5-methyl-1H-pyrrole-2-carboxylic acid (CAS 907545-39-5)
- 5-Bromo-6-chloro-3-methoxypyrazin-2-amine (CAS 566205-00-3)
- 4-Bromo-2-chloro-5-fluorobenzenemethanamine (CAS 1338432-69-1)
- 2-Bromo-6-chloro-4-fluoro-3-methylaniline (CAS 1365988-12-0)
Recommended Standards
- 3-Fluoro-5-(trichloromethyl)benzonitrile (CAS 1121586-25-1)
- 4-Chloropyridine-2,6-dicarbonyl dichloride (CAS 71022-75-8)
- 4,5,6-Trichlorobenzo[d]oxazol-2-ol (CAS 50995-94-3)
- 1-Heptadecene (CAS 6765-39-5)
- FCLA (CAS 133118-06-6)
- 2-(2,5-Dichlorophenyl)-1H-benzo[d]imidazole (CAS 14225-80-0)
- Sodium 3,4,5,6-tetrabromophthalate (CAS 25357-79-3)
- 4-methylcyclopentane-1,2-dicarboxylic acid (CAS 1597634-43-9)
- 2,5-Dioxopyrrolidin-1-yl 3-(2,4-di-tert-pentylphenoxy)propanoate (CAS 124709-46-2)
- 1-((2,4-Dichlorophenyl)sulfonyl)-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one (CAS 866050-07-9)
- 4-{6-[(4-methylphenyl)sulfanyl]-2-phenylpyrimidin-4-yl}morpholine (CAS 339018-75-6)
- 3-methylazetidine-3-carbonitrile hydrochloride (CAS 936850-33-8)
- Methyl 3-ethynyl-5-nitrobenzoate (CAS 1192472-44-8)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
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