3-[(3-Amino-1-piperidinyl)methyl]phenol dihydrochloride CAS 1158446-46-8
| CAS No. | 1158446-46-8 |
| Molecular Formula | C12H18N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-[(3-Amino-1-piperidinyl)methyl]phenol dihydrochloride (CAS 1158446-46-8), a certified reference material (molecular formula C12H18N2OHCl, MW 242.75 g/mol) for analytical method development and quality control.
The molecular framework of 3-[(3-Amino-1-piperidinyl)methyl]phenol dihydrochloride (C12H18N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H18N2O 2*HCl |
| Molecular Weight | 242.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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- 2-Amino-6-(3,4-dimethoxyphenyl)-4-(4-methoxyphenyl)pyridine-3-carbonitrile (CAS 235100-74-0)
- Methyl 5-(2-aminophenyl)furan-2-carboxylate (CAS 54023-14-2)
- 2-Chloro-1-(4-(3-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethan-1-one (CAS 260392-48-1)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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