6-Hydroxy-5-methylpyrimidine-4-carboxylic acid CAS 1159010-94-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Hydroxy-5-methylpyrimidine-4-carboxylic acid.

6-Hydroxy-5-methylpyrimidine-4-carboxylic acid (CAS 1159010-94-2), molecular formula C6H6N2O3 and molecular weight 154.12 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 6-Hydroxy-5-methylpyrimidine-4-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 154.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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