1-((Fluoromethyl)sulfonyl)-4-methylbenzene CAS 115909-68-7
| CAS No. | 115909-68-7 |
| Molecular Formula | C8H9FO2S |
| Molecular Weight | 188.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-((Fluoromethyl)sulfonyl)-4-methylbenzene.
1-((Fluoromethyl)sulfonyl)-4-methylbenzene (CAS 115909-68-7) is a high-purity analytical reference standard with the molecular formula C8H9FO2S and a molecular weight of 188.22 g/mol.
1-((Fluoromethyl)sulfonyl)-4-methylbenzene (C8H9FO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9FO2S |
| Molecular Weight | 188.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluoromethyl Standards
- (1-(Fluoromethyl)cyclopropyl)methanesulfonyl chloride (CAS 1314963-95-5)
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- 4-(Fluoromethyl)bicyclo[2.2.2]Octane-1-carboxylic acid (CAS 1350821-84-9)
- Methyl 4-(fluoromethyl)bicyclo[2.2.1]Heptane-1-carboxylate (CAS 1350822-05-7)
- 2-[4-(fluoromethyl)-1H-1,2,3-triazol-1-yl]-2-methylpropanoic acid (CAS 1934901-15-1)
- 2-[4-(fluoromethyl)-1H-1,2,3-triazol-1-yl]butanoic acid (CAS 1992992-00-3)
- 4-[4-(fluoromethyl)-1H-1,2,3-triazol-1-yl]butanoic acid (CAS 1992992-08-1)
- 3-(Fluoromethyl)-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazole-5-carboxylic acid (CAS 1263206-37-6)
Recommended Standards
- Ethyl 2-(propa-1,2-dien-1-yl)benzoate (CAS 1148131-98-9)
- (R)-1-((4R,5S)-2,2-Dimethyl-5-vinyl-1,3-dioxolan-4-yl)ethane-1,2-diol (CAS 116780-31-5)
- Ethyl N-[(2E)-2-(hydroxyimino)-1,1-dimethylethyl]-glycinate (CAS 1142202-27-4)
- 4-(3-Hydroxy-3-methylbut-1-yn-1-yl)benzaldehyde (CAS 117569-57-0)
- (5-Bromo-1-methyl-1H-pyrazol-3-yl)methanol (CAS 1782396-26-2)
- (R)-N-(1-(3-(8-Methyl-5-(methylamino)-8H-imidazo[4,5-d]thiazolo[5,4-b]pyridin-2-yl)phenyl)ethyl)-2-(methylsulfonyl)benzamide 1779493-12-7 (CAS 1779493-12-7)
- 4-(4-(Trifluoromethoxy)phenoxy)benzoic acid (CAS 617245-31-5)
- (Oxolan-3-ylmethyl)hydrazine dihydrochloride (CAS 1221722-22-0)
- 3-Isopropoxy-4-(trifluoromethoxy)phenylboronic acid (CAS 1793003-54-9)
- 3-Hydroxy-1,4-dihydroquinoxaline-2-carbaldehyde (CAS 855874-32-7)
- (R)-2-((4-(4-amino-2-fluorophenoxy)-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)amino)propan-1-ol (CAS 2412358-35-9)
- tert-Butyl 4-(2-chloroacetoxy)piperidine-1-carboxylate (CAS 1704122-01-9)
- 2-Bromo-1-fluoro-4-nitro-3-(trifluoromethyl)benzene (CAS 1421599-49-6)
- Tetrapeptide-30/Tegopep (CAS 1036207-61-0)
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