2-Bromo-3-chloroimidazo[1,2-a]pyridine CAS 1159511-19-9
| CAS No. | 1159511-19-9 |
| Molecular Formula | C7H4BrClN2 |
| Molecular Weight | 231.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Bromo-3-chloroimidazo[1,2-a]pyridine (CAS 1159511-19-9), molecular formula C7H4BrClN2 and molecular weight 231.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-3-chloroimidazo[1,2-a]pyridine (C7H4BrClN2) is characterized by a nitrile group, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-Bromo-3-chloroimidazo[1,2-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4BrClN2 |
| Molecular Weight | 231.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 3-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-39-5)
- 6-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-64-6)
- 3-Bromo-6-chloro-1H-pyrrolo[3,2-c]pyridine (CAS 1000341-61-6)
- 4-Bromo-7-chloro-1H-pyrrolo[3,2-c]pyridine (CAS 1000341-81-0)
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Recommended Standards
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- 7-Bromo-3-chloro-1H-pyrrolo[2,3-c]pyridine (CAS 1190309-88-6)
- Methyl 2-(4-oxo-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-3(4h)-yl)acetate (CAS 450376-42-8)
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- 8-(2-Octylcyclopropyl)octanoic acid (CAS 5711-28-4)
- (4-Iodo-2-nitrophenyl)hydrazine (CAS 89640-59-5)
- Methyl hexanimidate hydrochloride (CAS 17465-87-1)
- 3-Methyl-1H-pyrazol-5-amine (CAS 113402-89-4)
- 2-Bromo-6-(trimethylsilyl)phenyl triflate (CAS 1092542-31-8)
- 3-(5-((Diethylamino)methyl)thiophen-3-yl)prop-2-yn-1-amine (CAS 1251125-90-2)
- [(4-Formyl-2-nitrophenyl)sulfanyl]acetic acid (CAS 384856-42-2)
- Neuropeptide W-23 (rat) (CAS 383415-89-2)
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