5-amino-1-(5-fluoro-2-methylphenyl)-1H-pyrazole-4-carbonitrile CAS 1159678-19-9
| CAS No. | 1159678-19-9 |
| Molecular Formula | C11H9FN4 |
| Molecular Weight | 216.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-amino-1-(5-fluoro-2-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1159678-19-9), molecular formula C11H9FN4 and molecular weight 216.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-amino-1-(5-fluoro-2-methylphenyl)-1H-pyrazole-4-carbonitrile (C11H9FN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 5-amino-1-(5-fluoro-2-methylphenyl)-1H-pyrazole-4-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9FN4 |
| Molecular Weight | 216.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related amino Standards
- 5-Amino-1-(2-fluorophenyl)-3-methyl-1h-pyrazole-4-carbonitrile (CAS 1072944-83-2)
- 5-Amino-1-(3-fluoro-2-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1159678-33-7)
- 5-Amino-1-(4-fluoro-2-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1159678-53-1)
- 5-Amino-1-(3-fluoro-4-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1416344-54-1)
- 2-Amino-4-(aminosulfonyl)benzenecarboxylic acid (CAS 25096-72-4)
- 2-Amino-5-nitro-thiophene-3-carboxylic acid ethyl ester (CAS 42783-04-0)
- 3-amino-4-sulfamoylbenzoic acid (CAS 89694-27-9)
- 4-Amino-2-sulfamoylbenzoic acid (CAS 46277-93-4)
Recommended Standards
- 2-(((1h-Pyrazol-3-yl)methyl)amino)-6-fluorobenzonitrile (CAS 1156316-45-8)
- 2-Fluoro-4-phenoxybenzaldehyde (CAS 1133065-51-6)
- 2-Fluoro-N-(pyridin-4(1h)-ylidene)benzamide (CAS 113204-23-2)
- (E)-3-(2-fluorophenyl)-1-(furan-3-yl)prop-2-en-1-one (CAS 1164555-67-2)
- 4-Chloro-2,5-difluoropyridine-3-carboxylic acid (CAS 851386-42-0)
- 1-(2-Bromo-4-fluorophenyl)pyrrolidin-2-one (CAS 1037150-18-7)
- 6-(2-Chloro-4-fluorophenyl)-6-oxohexanoic acid (CAS 951889-44-4)
- N-(4-(Benzofuran-2-yl)thiazol-2-yl)-3-phenylpropanamide (CAS 923504-47-6)
- 2-Isopropylpyrimidine-4,5-diamine (CAS 1237537-51-7)
- 2,4-Dimethyl-6-nitro-benzoic acid (CAS 1379173-92-8)
- 3,4,5,6-Tetrafluorobenzene-1,2-diamine (CAS 2993-07-9)
- Vortioxetine Impurity 67 (CAS CATO-C4X-105667)
- Methyl 2-(3-cyano-4-nitrophenyl)-2-(2-methoxyphenyl)acetate (CAS 1980045-02-0)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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