Tert-butyl 3-(2,2,2-trifluoroacetyl)pyrrolidine-1-carboxylate CAS 1159981-92-6
| CAS No. | 1159981-92-6 |
| Molecular Formula | C11H16F3NO3 |
| Molecular Weight | 267.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Tert-butyl 3-(2,2,2-trifluoroacetyl)pyrrolidine-1-carboxylate (CAS 1159981-92-6), molecular formula C11H16F3NO3 and molecular weight 267.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Tert-butyl 3-(2,2,2-trifluoroacetyl)pyrrolidine-1-carboxylate (C11H16F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H16F3NO3 |
| Molecular Weight | 267.24 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-(4-Nitrophenyl)-1H-indene-1,3(2H)-dione (CAS 1153-90-8)
- 1-BOC-3-trifluoromethyl-piperidin-4-one (CAS 1159983-77-3)
- 3-((2-Amino-6-oxo-1H-purin-9(6H)-yl)oxy)propyl acetate (CAS 114778-61-9)
- 2-Amino-9-((2S,4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one (CAS 116002-28-9)
- 1-(4-Amino-3-ethylpiperidin-1-yl)ethan-1-one (CAS 1423117-17-2)
- 6-(Pyrrolidin-1-yl)hexan-2-amine (CAS 1248063-30-0)
- 5-(Trifluoromethyl)-2,3-dihydrobenzo[b]thiophene-2-carboxylic acid (CAS 1306604-87-4)
- 6-Amino-2-fluoro-N,N-dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 2244517-33-5)
- Potassium 2-(pyrazin-2-yl)acetate (CAS 1251919-99-9)
- CG-806 (CAS 1370466-81-1)
- 2-(Difluoromethyl)-6-hydroxy-5-(trifluoromethoxy)pyridine-3-acetic acid (CAS 1806160-69-9)
- 3A,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-yl butyrate (CAS 17511-61-4)
- 2-Amino-5-fluoroquinazoline (CAS 190273-81-5)
- Smac-N7 Peptide (CAS 401913-57-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com