2-(1-(2,2,2-Trifluoroethyl)piperidin-4-yl)acetic acid CAS 1159983-47-7
| CAS No. | 1159983-47-7 |
| Molecular Formula | C9H14F3NO2 |
| Molecular Weight | 225.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(1-(2,2,2-Trifluoroethyl)piperidin-4-yl)acetic acid (CAS 1159983-47-7) is a high-purity analytical reference standard with the molecular formula C9H14F3NO2 and a molecular weight of 225.21 g/mol.
The molecular framework of 2-(1-(2,2,2-Trifluoroethyl)piperidin-4-yl)acetic acid (C9H14F3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 2-(1-(2,2,2-Trifluoroethyl)piperidin-4-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H14F3NO2 |
| Molecular Weight | 225.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoroethyl Standards
- 2,2,2-Trifluoroethyl 4-methylpiperidine-1-carboxylate (CAS 1092074-38-8)
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- 8-(2,2,2-Trifluoroethyl)-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 710350-66-6)
- 5-Propyl-4-(2,2,2-trifluoroethyl)-4h-1,2,4-triazole-3-thiol (CAS 1038323-81-7)
- 4-Methyl-2-(2,2,2-trifluoroethyl)-1,3-thiazole-5-carboxylic acid (CAS 1248235-40-6)
- 2,2,2-trifluoroethyl N-(thiophen-2-yl)carbamate (CAS 1305712-70-2)
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Recommended Standards
- 2-(Pyridin-4-yl)pteridin-4(3H)-one (CAS 1092305-65-1)
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- (S)-2,2,2-trifluoro-1-(naphthalen-1-yl)ethanamine (CAS 1213116-97-2)
- (3,4-Difluorophenyl)(thiazol-2-yl)methanone (CAS 1086277-36-2)
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- 1-(2-Chloro-4-(trifluoromethyl)phenyl)piperazine (CAS 847971-80-6)
- (1,3-benzothiazol-2-ylthio)acetonitrile (CAS 24793-01-9)
- (2S,3R)-4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid (CAS 1234694-22-4)
- 6-Nitrodopamine (CAS 21581-49-7)
- 3H-imidazo[4,5-b]pyridine-7-carboxylic acid (CAS 78316-08-2)
- 4-Fluoro-N-(3-methoxybenzylidene)aniline (CAS 202073-14-1)
- Methyl 2-(benzyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1073355-16-4)
- 3-(4-(4-Methoxybenzylidene)-2,3-dioxopyrrolidin-1-yl)propanoic acid (CAS 76628-84-7)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
Why CATO?
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