8-Chloro-2-(5-methyl-2-thienyl)quinoline-4-carbonyl chloride CAS 1160256-80-3
| CAS No. | 1160256-80-3 |
| Molecular Formula | C15H9Cl2NOS |
| Molecular Weight | 322.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-Chloro-2-(5-methyl-2-thienyl)quinoline-4-carbonyl chloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-Chloro-2-(5-methyl-2-thienyl)quinoline-4-carbonyl chloride (CAS 1160256-80-3), molecular formula C15H9Cl2NOS and molecular weight 322.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Chloro-2-(5-methyl-2-thienyl)quinoline-4-carbonyl chloride (C15H9Cl2NOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Chloro-2-(5-methyl-2-thienyl)quinoline-4-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H9Cl2NOS |
| Molecular Weight | 322.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-(5-Chloro-2-thienyl)-6-methylquinoline-4-carbonyl chloride (CAS 1160253-37-1)
- 2-(5-Chloro-2-thienyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160254-07-8)
- 7-Chloro-8-methyl-2-(2-thienyl)quinoline-4-carbonyl chloride (CAS 1160256-79-0)
- 6-Chloro-2-(5-methyl-2-thienyl)quinoline-4-carbonyl chloride (CAS 1160263-07-9)
- 1000575-73-4 2-Chloro-N-(2-chlorophenyl)-2-[2-(4-methylphenyl)hydrazono]acetamide MFCD09877858 (CAS 1000575-73-4)
- 2-Chloro-9-(4-chlorobenzyl)-N,N-dimethyl-9H-purin-6-amine (CAS 115204-54-1)
- 2-Chloro-9-(3-chlorobenzyl)-N,N-dimethyl-9H-purin-6-amine (CAS 115204-64-3)
- 7-Chloro-4-[(4-chlorophenyl)methyl]-2,3,4,5-tetrahydro-1,4-benzoxazepin-3-one (CAS 1340932-45-7)
Recommended Standards
- tert-Butyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate (CAS 1220967-98-5)
- 1-(3-chlorobenzoyl)piperidine-3-sulfonyl chloride (CAS 1461705-29-2)
- Formoterol Impurity 56 (CAS 333796-54-6)
- 2-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-yl]-propionic acid tert-butyl ester (CAS 1940181-88-3)
- 1-(5-Bromothiophen-2-yl)-3-ethoxyprop-2-en-1-one (CAS 1344886-67-4)
- (3AS,8bS)-7-bromo-3a,8b-dihydro-3H-cyclopenta[b]benzofuran-5-carboxylic acid (CAS 88277-50-3)
- 5,10,15-TRis(4-tert-butylphenyl) corrole (CAS 958259-08-0)
- 5-amino-7-(4-fluorobenzyl)-9-hydroxy-6H-pyrrolo[3,4-g]quinoline-6,8(7H)-dione (CAS 915690-75-4)
- 4-Oxo-4-(8-oxo-1,5,6,8-tetrahydro-2h-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4h)-yl)butanoic acid (CAS 904209-40-1)
- 1-[3-Chloro-5-(trifluoromethyl)phenyl]cyclopentanemethanamine (CAS 1896976-40-1)
- 3-[[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]amino]-3-oxo-propanoic acid (CAS 2353496-81-6)
- Cefixime Impurity 74 (CAS CATO-C4X-113974)
- 3-Aminomethyl-3-(hydroxymethyl)oxetane oxalate (CAS 1434142-00-3)
- Retatrutide (CAS 2381089-83-2)
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