5-Chloro-2-[(2-chloro-6-fluorobenzyl)oxy]-benzoyl chloride CAS 1160260-41-2
| CAS No. | 1160260-41-2 |
| Molecular Formula | C14H8Cl3FO2 |
| Molecular Weight | 333.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2-[(2-chloro-6-fluorobenzyl)oxy]-benzoyl chloride is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-2-[(2-chloro-6-fluorobenzyl)oxy]-benzoyl chloride (CAS 1160260-41-2), a certified reference material (molecular formula C14H8Cl3FO2, MW 333.57 g/mol) for analytical method development and quality control.
Based on its molecular formula C14H8Cl3FO2, 5-Chloro-2-[(2-chloro-6-fluorobenzyl)oxy]-benzoyl chloride contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 333.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl3FO2 |
| Molecular Weight | 333.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-2-[(2-chloro-4-fluorobenzyl)oxy]-benzoyl chloride (CAS 1160260-39-8)
- 8-Chloro-3-(cyclopropylmethyl)-7-iodo-[1,2,4]triazolo[4,3-a]pyridine (CAS 1254981-17-3)
- 4-Chloro-1-(4-iodobenzyl)-1h-pyrazol-3-amine (CAS 1484509-81-0)
- 8-Chloro-3-cyclobutyl-1-iodoimidazo[1,5-a]pyrazine (CAS 867165-15-9)
- 7-Chloro-3-iodo-2,8-dimethylquinolin-4(1H)-one (CAS 1330754-14-7)
- 4-Chloro-5-((2,4-dichlorobenzyl)oxy)-2-ethylpyridazin-3(2H)-one (CAS 88094-01-3)
- 4-Chloro-5-((3,4-dichlorobenzyl)oxy)-2-ethylpyridazin-3(2H)-one (CAS 88094-02-4)
- 3-Chloro-2-(3-fluorophenyl)-5-iodopyridine (CAS 1214384-24-3)
Recommended Standards
- 3,5-Dichloro-2-((2-chloro-6-fluorobenzyl)oxy)benzaldehyde (CAS 1410967-54-2)
- 1,3-Dimethoxy-6,7-bis(trimethylsilyl)isoquinoline (CAS 86854-63-9)
- 5-Bromo-4-chloro-6-(5-fluorofuran-2-yl)thieno[2,3-d]pyrimidine (CAS 1799610-97-1)
- 11-(Triethoxysilyl)undecan-1-amine (CAS 116821-45-5)
- 2-((3,5-Dimethylcyclohexyl)oxy)ethane-1-sulfonyl chloride (CAS 1343073-94-8)
- (1S,4s)-4-amino-N-methylcyclohexane-1-carboxamide hydrochloride (CAS 2270911-51-6)
- 4-Bromo-2-methylbenzofuran-7-carboxylic acid (CAS 1797928-84-7)
- 1-({4-chloro-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl}methyl)pyrrolidine (CAS 733794-76-8)
- (R)-3-(2-methoxyphenoxy)butanoic acid (CAS 1416445-13-0)
- 2-(2,3-Dichlorophenoxy)-3,3,3-trifluoropropan-1-amine (CAS 886764-19-8)
- N-(2-(4-Bromophenyl)propyl)propane-2-sulfonamide (CAS 211311-65-8)
- 1-(4-Nitrophenyl)cyclopentane-1-carboxylic acid (CAS 52648-77-8)
- (5-Fluoropyridin-2-yl)methanamine hydrochloride (CAS 1228788-32-6)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
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