2-(4-sec-Butylphenyl)-6,8-dimethylquinoline-4-carbonyl chloride CAS 1160262-75-8
| CAS No. | 1160262-75-8 |
| Molecular Formula | C22H22ClNO |
| Molecular Weight | 351.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(4-sec-Butylphenyl)-6,8-dimethylquinoline-4-carbonyl chloride (CAS 1160262-75-8), a certified reference material (molecular formula C22H22ClNO, MW 351.87 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4-sec-Butylphenyl)-6,8-dimethylquinoline-4-carbonyl chloride (C22H22ClNO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22ClNO |
| Molecular Weight | 351.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related sec Standards
- 2-(4-tert-Butylphenyl)-6-ethylquinoline-4-carbonyl chloride (CAS 1160260-95-6)
- 2-(4-Butylphenyl)-6,8-dimethylquinoline-4-carbonyl chloride (CAS 1160262-71-4)
- 2-(4-tert-Butylphenyl)-6,8-dimethylquinoline-4-carbonyl chloride (CAS 1160262-73-6)
- N-(4-butylphenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 868256-44-4)
- N-(4-(4-butylphenyl)thiazol-2-yl)-2-phenylacetamide (CAS 866049-67-4)
- 2-{3-[(4-tert-butylphenyl)methyl]-4-oxo-3,4-dihydrophthalazin-1-yl}acetic acid (CAS 866151-30-6)
- 2-[(4-tert-Butylphenyl)methoxy]-5-(phenoxymethyl)-1,3-thiazole (CAS 339105-23-6)
- 5-(4-Tert-butylphenyl)-4-(4-ethoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 731802-52-1)
Recommended Standards
- 4-[(3,5-dimethylpiperidin-1-yl)sulfonyl]benzene-1-sulfonyl chloride (CAS 1258650-42-8)
- 2-(4-Isobutylphenyl)-6,8-dimethylquinoline-4-carbonyl chloride (CAS 1160262-72-5)
- 1-(4-Chlorophenyl)-2-((4-methylbenzyl)amino)-1-phenylethan-1-ol (CAS 306977-70-8)
- 4-(2-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)benzoic acid (CAS 4113-88-6)
- 3-Hydroxy-2-(hydroxymethyl)-2-methylpropanal (CAS 18516-18-2)
- 2-(M-tolyl)acetimidamide (CAS 802557-83-1)
- 1,2,3-Trimethoxypropane (CAS 20637-49-4)
- 4-(3-Formylphenyl)-1-methoxyisoquinolin-5-yl benzoate (CAS 651030-48-7)
- Phloroacetophenone 4-O-β-D-glucopyranoside (CAS 5027-30-5)
- 6-Bromo-7-methylisobenzofuran-1(3H)-one (CAS 1179360-30-5)
- 7'-Fluoro-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-isoquinoline] (CAS 1283718-61-5)
- Mifepristone-d3 (CAS CATO-C4X-12164)
- 4-Bromo-5-(trifluoromethyl)-1H-1,2,3-triazole (CAS 1823347-99-4)
- Semaglutide impurity 235 (CAS CATO-C4X-2226235)
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