8-Chloro-2-(3-methylphenyl)quinoline-4-carbonyl chloride CAS 1160263-53-5
| CAS No. | 1160263-53-5 |
| Molecular Formula | C17H11Cl2NO |
| Molecular Weight | 316.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 8-Chloro-2-(3-methylphenyl)quinoline-4-carbonyl chloride (C17H11Cl2NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
8-Chloro-2-(3-methylphenyl)quinoline-4-carbonyl chloride (CAS 1160263-53-5) is a high-purity analytical reference standard with the molecular formula C17H11Cl2NO and a molecular weight of 316.18 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Chloro-2-(3-methylphenyl)quinoline-4-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H11Cl2NO |
| Molecular Weight | 316.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2-(4-methylphenyl)quinoline-4-carbonyl chloride (CAS 103914-62-1)
- 8-Chloro-3-methyl-2-phenylquinoline-4-carbonyl chloride (CAS 1160256-96-1)
- 6-Chloro-2-(2-methylphenyl)quinoline-4-carbonyl chloride (CAS 1160263-11-5)
- 6-Chloro-2-(3-methylphenyl)quinoline-4-carbonyl chloride (CAS 1160263-12-6)
- 8-Chloro-2-(4-methylphenyl)quinoline-4-carbonyl chloride (CAS 1160263-51-3)
- 8-Chloro-2-(2-methylphenyl)quinoline-4-carbonyl chloride (CAS 1160263-55-7)
- 1-(2-Chloro-4-(4-chlorophenyl)quinolin-3-yl)ethan-1-one (CAS 1376314-02-1)
- (1E)-1-(5-Chloro-2-phenyl-1H-imidazol-4-yl)-N-(4-chlorophenyl)methanimine (CAS 860787-98-0)
Recommended Standards
- 2-(4-Chlorophenyl)-3-methylquinoline-4-carbonyl chloride (CAS 1160264-95-8)
- 2-(3-Chlorophenyl)-3-methylquinoline-4-carbonyl chloride (CAS 1160264-96-9)
- n-((4-Bromothiophen-2-yl)methyl)-N-methyl-2-(1h-tetrazol-1-yl)acetamide (CAS 1211291-83-6)
- 2-(4-Chlorophenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160254-33-0)
- rel-tert-Butyl (3R,4R)-3-fluoro-4-(2-oxoethyl)piperidine-1-carboxylate (CAS 2839758-85-7)
- 2-(5-ethylfuran-2-yl)azepane (CAS 1333890-80-4)
- 4-[2-(2,6-dioxo-3-piperidyl)-3-oxo-isoindolin-5-yl]butanoic acid (CAS 2767163-50-6)
- 2-(2-Hydrazinylpyridin-4-yl)-4-phenylthiazole (CAS 1707727-53-4)
- 1-Benzyl-1H-benzimidazole-2-thiol (CAS 31493-51-3)
- 5-(tert-Butyl)-4-cyclopropoxy-2-ethylpyridine (CAS 1243368-55-9)
- [(2,4-dimethylphenyl)thio]acetic acid (CAS 75243-12-8)
- 2-(2-Chlorophenoxy)-4-methylthiazole-5-carboxylic acid (CAS 1232801-51-2)
- 2-[2-(trifluoromethyl)benzenesulfonamido]propanoic acid (CAS 1008938-50-8)
- Vancomycin Hexapeptide (CAS 115236-65-2)
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