8-Chloro-2-(3-ethoxyphenyl)quinoline-4-carbonyl chloride CAS 1160263-73-9
| CAS No. | 1160263-73-9 |
| Molecular Formula | C18H13Cl2NO2 |
| Molecular Weight | 346.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Chloro-2-(3-ethoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-73-9) is a high-purity analytical reference standard with the molecular formula C18H13Cl2NO2 and a molecular weight of 346.21 g/mol.
8-Chloro-2-(3-ethoxyphenyl)quinoline-4-carbonyl chloride (C18H13Cl2NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Chloro-2-(3-ethoxyphenyl)quinoline-4-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H13Cl2NO2 |
| Molecular Weight | 346.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2-(4-ethoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-33-1)
- 6-Chloro-2-(3-ethoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-34-2)
- 6-Chloro-2-(2-ethoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-36-4)
- 7-Chloro-2-(4-methoxyphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160263-66-0)
- 7-Chloro-2-(3-methoxyphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160263-68-2)
- 7-Chloro-2-(2-methoxyphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160263-70-6)
- 8-Chloro-2-(4-ethoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-71-7)
- 8-Chloro-2-(2-ethoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-75-1)
Recommended Standards
- 2,4-Dichloro-5-(isopropoxycarbonyl)phenyl pyrrolidine-1-carboxylate (CAS 133636-96-1)
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- (S)-2-Amino-N-(2-iodobenzyl)-N-isopropylpropanamide (CAS 1353996-51-6)
- (S)-2-Amino-N-(2-iodobenzyl)-N,3-dimethylbutanamide (CAS 1354020-53-3)
- 2,3-Bis(piperidin-1-yl)quinoxaline (CAS 75163-14-3)
- tert-Butyl (2-(2-(4-(2-hydroxyethoxy)butoxy)ethoxy)ethyl)carbamate (CAS 2681390-76-9)
- cis-3-[2-(2-Methoxyphenyl)-2-oxoethyl]-cyclohexane-1-carboxylic acid (CAS 735275-08-8)
- 3-(4-Fluoro-2-methylphenyl)-2-oxopropanoic acid (CAS 1249266-47-4)
- 5-(1-Methyl-1h-pyrazol-4-yl)nicotinaldehyde (CAS 342601-28-9)
- 4-(1-Ethyl-1h-pyrazol-5-yl)butan-2-ol (CAS 1339664-60-6)
- 6-Bromo-3-methoxy-2-methylpyridine, 97% (CAS 850882-87-0)
- (2-Methylpyridin-4-yl)(4-(trifluoromethyl)phenyl)methanone (CAS 1187165-08-7)
- Methyl 5-((diethylamino)methyl)furan-2-carboxylate (CAS 24653-40-5)
- Insulin Glargine (CAS 160337-95-1)
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