8-Chloro-2-(4-propoxyphenyl)quinoline-4-carbonyl chloride CAS 1160263-77-3
| CAS No. | 1160263-77-3 |
| Molecular Formula | C19H15Cl2NO2 |
| Molecular Weight | 360.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 8-Chloro-2-(4-propoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-77-3), a certified reference material (molecular formula C19H15Cl2NO2, MW 360.23 g/mol) for analytical method development and quality control.
Structurally, 8-Chloro-2-(4-propoxyphenyl)quinoline-4-carbonyl chloride (C19H15Cl2NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 360.23 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Chloro-2-(4-propoxyphenyl)quinoline-4-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H15Cl2NO2 |
| Molecular Weight | 360.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2-(4-propoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-37-5)
- 6-Chloro-2-(4-isopropoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-39-7)
- 6-Chloro-2-(3-propoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-42-2)
- 6-Chloro-2-(3-isopropoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-43-3)
- 6-Chloro-2-(2-propoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-47-7)
- 6-Chloro-2-(2-isopropoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-49-9)
- 7-Chloro-2-(4-ethoxyphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160263-72-8)
- 7-Chloro-2-(3-ethoxyphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160263-74-0)
Recommended Standards
- 7-Chloro-2-(2-ethoxyphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160263-76-2)
- 8-Chloro-2-(3-propoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-79-5)
- 8-Chloro-2-(4-isopropoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-81-9)
- 8-Chloro-2-(3-isopropoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-83-1)
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- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
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