7-Chloro-2-(3-isopropoxyphenyl)-8-methylquinoline-4-carbonyl chloride CAS 1160263-84-2
| CAS No. | 1160263-84-2 |
| Molecular Formula | C20H17Cl2NO2 |
| Molecular Weight | 374.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Chloro-2-(3-isopropoxyphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160263-84-2), molecular formula C20H17Cl2NO2 and molecular weight 374.26 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 7-Chloro-2-(3-isopropoxyphenyl)-8-methylquinoline-4-carbonyl chloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 374.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17Cl2NO2 |
| Molecular Weight | 374.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 8-Chloro-2-(4-isobutoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160255-90-2)
- 8-Chloro-2-(3-isobutoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160255-98-0)
- 6-Chloro-2-(4-isobutoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-41-1)
- 6-Chloro-2-(3-isobutoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-45-5)
- 7-Chloro-8-methyl-2-(4-propoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-78-4)
- 7-Chloro-8-methyl-2-(3-propoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-80-8)
- 7-Chloro-2-(4-isopropoxyphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160263-82-0)
- 2-(2-Chloro-4-(trifluoromethyl)phenyl)-5-(2-chlorophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000575-12-1)
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