3,5-Dibromo-2-fluoro-6-iodobenzoic acid CAS 1160573-45-4
| CAS No. | 1160573-45-4 |
| Molecular Formula | C7H2Br2FIO2 |
| Molecular Weight | 423.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3,5-Dibromo-2-fluoro-6-iodobenzoic acid (CAS 1160573-45-4) is a high-purity analytical reference standard with the molecular formula C7H2Br2FIO2 and a molecular weight of 423.80 g/mol.
The molecular framework of 3,5-Dibromo-2-fluoro-6-iodobenzoic acid (C7H2Br2FIO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H2Br2FIO2 |
| Molecular Weight | 423.80 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Br/I-containing |
Related Dibromo Standards
- 2,3-Dibromo-6-fluoro-5-iodobenzoic acid (CAS 1160573-40-9)
- 4,6-Dibromo-2-fluoro-3-iodobenzoic acid (CAS 1160573-42-1)
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- 5-Bromo-2-chloro-4-(trifluoromethyl)thiazole (CAS 1289049-22-4)
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