4-Chloro-5-iodo-6-methylnicotinonitrile CAS 1160848-89-4
| CAS No. | 1160848-89-4 |
| Molecular Formula | C7H4ClIN2 |
| Molecular Weight | 278.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Chloro-5-iodo-6-methylnicotinonitrile (CAS 1160848-89-4), molecular formula C7H4ClIN2 and molecular weight 278.48 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, chlorine/iodine substitution, an aromatic ring system, 4-Chloro-5-iodo-6-methylnicotinonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 278.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4-Chloro-5-iodo-6-methylnicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4ClIN2 |
| Molecular Weight | 278.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-7-iodo-1H-indazole (CAS 1000341-92-3)
- 4-Chloro-5-iodo-1H-indazole (CAS 1000342-37-9)
- 7-Chloro-5-iodo-1H-indazole (CAS 1000343-56-5)
- 6-Chloro-8-iodoimidazo[1,2-a]pyridine (CAS 1033463-28-3)
- 5-Chloro-2-iodo-6-methylnicotinonitrile (CAS 1163297-84-4)
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Recommended Standards
- 2-Amino-5-chloro-3-iodobenzonitrile (CAS 1000577-48-9)
- 3-Chloro-4-iodo-1h-pyrrolo[2,3-b]pyridine (CAS 1190313-54-2)
- (3,5-difluorobenzyl)zinc(II) bromide 3,5-Difluorobenzylzinc bromide 308796-30-7 (CAS 308796-30-7)
- 7-Chloro-3-iodo-1H-pyrrolo[2,3-c]pyridine (CAS 1190314-63-6)
- Methyl 2-mercapto-4-methylbenzoate (CAS 345910-55-6)
- 2-(2-bromophenyl)but-3-yn-2-ol (CAS 104684-12-0)
- 4-(4-Piperidinyl)pyrimidine (CAS 954220-47-4)
- Diphenyl-pyrrolidin-3-yl-methanol (CAS 5731-19-1)
- H-His-Tyr-OH (CAS 35979-00-1)
- 2,2'-(hexadecylazanediyl)diethanol (CAS 18924-67-9)
- (4-Bromo-6-methoxy-2-(trifluoromethyl)-1,5-naphthyridin-3-yl)boronic acid (CAS 1565779-85-2)
- 2-(tert-Butoxycarbonyl)benzo[b]thiophene-5-carboxylic acid (CAS 2502300-24-3)
- 4-Bromo-5-chloro-1-methylpyridin-2(1H)-one (CAS 1785263-12-8)
- Allo-D-Ile17-Tirzepatide (CAS CATO-CPTD788962)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com