2-Chloro-4-iodophenol CAS 116130-33-7
| CAS No. | 116130-33-7 |
| Molecular Formula | C6H4ClIO |
| Molecular Weight | 254.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 254.45 g/mol gives 2-Chloro-4-iodophenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-4-iodophenol (CAS 116130-33-7), molecular formula C6H4ClIO and molecular weight 254.45 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-4-iodophenol (C6H4ClIO) is characterized by a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-4-iodophenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4ClIO |
| Molecular Weight | 254.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/I-containing |
Related Chloro Standards
- 5-Chloro-2-iodophenol (CAS 136808-72-5)
- 2-Chloro-3-iodophenol (CAS 666727-31-7)
- 2-Chloro-5-iodophenol (CAS 289039-26-5)
- 3-Chloro-2-iodophenol (CAS 858854-82-7)
- 3-Chloro-4-iodophenol (CAS 855403-42-8)
- 3-Chloro-5-iodophenol (CAS 861347-86-6)
- 4-Chloro-2-iodophenol, 98% (CAS 71643-66-8)
- 4-Chloro-3-iodophenol (CAS 202982-72-7)
Recommended Standards
- Procaine Impurity 21 (CAS CATO-C4X-262321)
- 2-Chloro-6-iodophenol (CAS 28177-52-8)
- (2-phenylethane-1,1-diyl)bis(propylsulfane) (CAS CATO-C3D-262380)
- 2-Chloro-6-iodopyridin-3-amine (CAS 1032507-20-2)
- Tert-butyl 2-(dihydrofuran-3(2H)-ylidene)hydrazine-1-carboxylate (CAS 158020-60-1)
- 2,2,3,3-Tetrafluoropropyl 2,2-difluoroacetate (CAS 1365808-08-7)
- 1,2-Di(pyridin-4-yl)ethyne (CAS 73564-69-9)
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- 3-Fluoro-4-hydroxy-1-piperidinecarboxylic Acid tert-Butyl Ester(Mixture of Diastereomers) (CAS 373604-28-5)
- 11-cis-Acitretin (CAS 1067630-53-8)
- 4-Aminobiphenyl-D9 (CAS 344298-96-0)
- Angiotensin II Antipeptide (CAS 121379-63-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com