(3r,4s)-4-(2-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid CAS 1161787-74-1
| CAS No. | 1161787-74-1 |
| Molecular Formula | C16H20BrNO4 |
| Molecular Weight | 370.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (3r,4s)-4-(2-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(3r,4s)-4-(2-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid (CAS 1161787-74-1) is a high-purity analytical reference standard with the molecular formula C16H20BrNO4 and a molecular weight of 370.24 g/mol.
The molecular framework of (3r,4s)-4-(2-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid (C16H20BrNO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H20BrNO4 |
| Molecular Weight | 370.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (3aS,4R,9bR)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline (G-15) (CAS 1161002-05-6)
- Boc-trans-DL-β-Pro-4-(4-bromophenyl)-OH (CAS 1217829-96-3)
- Methyl2-(4-bromophenyl)-1-((tert-Butoxycarbonyl)amino)cyclopropane-1-carboxylate (CAS 1092460-42-8)
- 3-Bromo-8-methoxy-6,6-dimethyl-5H-benzo[b]carbazol-11(6H)-one (CAS 1256576-68-7)
- Sodium 2,3,4,5,6-pentafluorobenzoate (CAS 4830-57-3)
- tert-Butyl(phenylsulfonyl)glycinate (CAS 34545-74-9)
- (R)-Benzyl (1-(2-hydroxyethyl)pyrrolidin-3-yl)(isopropyl)carbamate (CAS 1354019-53-6)
- N-(4-((Methylthio)methyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide (CAS 942009-72-5)
- (4-Fluoro-3-methylphenyl)(2-iodophenyl)methanone (CAS 951886-62-7)
- 1,6-Dimethyl-1,2,3,4-tetrahydroquinoxaline (CAS 912284-80-1)
- 3-Cyclopentyl-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 1033444-00-6)
- 2-Methyl-6-(trifluoromethyl)pyrimidin-4-amine (CAS 54518-10-4)
- 2283AE 387824-55-7 5-[4-(Trifluoromethyl)phenyl]isoxazole C10H6F3NO (CAS 387824-55-7)
- Insulin Glulisine (CAS 207748-29-6)
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