6-Methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid CAS 1161833-78-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1161833-78-8
Molecular FormulaC11H13NO3
Molecular Weight207.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid CAS 1161833-78-8 chemical structure

Description

6-Methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (C11H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

6-Methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 1161833-78-8), molecular formula C11H13NO3 and molecular weight 207.23 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H13NO3
Molecular Weight207.23 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Nitrogen Atoms1

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