4-(Difluoromethoxy)-3-fluorophenylboronic Acid Pinacol Ester CAS 1162262-35-2
| CAS No. | 1162262-35-2 |
| Molecular Formula | C13H16BF3O3 |
| Molecular Weight | 288.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(Difluoromethoxy)-3-fluorophenylboronic Acid Pinacol Ester (CAS 1162262-35-2), molecular formula C13H16BF3O3 and molecular weight 288.07 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C13H16BF3O3, 4-(Difluoromethoxy)-3-fluorophenylboronic Acid Pinacol Ester contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 288.07 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-(Difluoromethoxy)-3-fluorophenylboronic Acid Pinacol Ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16BF3O3 |
| Molecular Weight | 288.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Difluoromethoxy Standards
- 2-(2-(Difluoromethoxy)-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1403988-78-2)
- 2-(2-(Difluoromethoxy)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1417301-27-9)
- 2-(5-(Difluoromethoxy)-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1445600-93-0)
- 4-Difluoromethoxy-2-fluorobenzeneboronic acid pinacol ester, 97% (CAS 1628442-55-6)
- 2-(3-(Difluoromethoxy)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1641578-50-8)
- 2-(3-(Difluoromethoxy)-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1641580-18-8)
- 2-(2-(Difluoromethoxy)-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2621936-65-8)
- 2-(2-(Difluoromethoxy)-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2375423-84-8)
Recommended Standards
- 3-(4-Bromo-2-fluorophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 1094502-97-2)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)phenol (CAS 1243143-45-4)
- 3-(5-Bromo-2-fluorophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 1038715-38-6)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)phenol (CAS 1256944-93-0)
- (E)-3-(4-Chlorostyryl)-1H-pyrazole (CAS 1829580-37-1)
- Bis(2-thienylmethyl)amine Hydrochloride (CAS 58703-21-2)
- 2-Phenyl-5,6,7,8-tetrahydroquinazolin-6-amine dihydrochloride (CAS 1193389-46-6)
- (4-fluoropyrrolidin-2-yl)methanol hydrochloride (CAS 1798012-86-8)
- 4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (CAS 1422268-43-6)
- S-Benzyl ethanethioate (CAS 32362-99-5)
- 4-Amino-N-(4-carbamoylphenyl)benzamide (CAS 74441-06-8)
- 3-Methyl-5-(2-methylprop-1-en-1-yl)isoxazole (CAS 101246-24-6)
- 2-Cyclopropyl-2-methylpropanal (CAS 1936689-91-6)
- Valosin Peptide (VQY), porcine (CAS 99510-37-9)
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