N-Methylisoxazole-5-carboxamide CAS 116235-70-2
| CAS No. | 116235-70-2 |
| Molecular Formula | C5H6N2O2 |
| Molecular Weight | 126.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-Methylisoxazole-5-carboxamide (CAS 116235-70-2), a certified reference material (molecular formula C5H6N2O2, MW 126.11 g/mol) for analytical method development and quality control.
The molecular framework of N-Methylisoxazole-5-carboxamide (C5H6N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6N2O2 |
| Molecular Weight | 126.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Related N Standards
- 5-Methylisoxazole-4-carboxamide (CAS 1097817-28-1)
- 3-Methylisoxazole-4-carboxamide (CAS 1314959-75-5)
- 3-Methylisoxazole-5-carboxamide (CAS 38955-11-2)
- 4-Methylisoxazole-3-carboxamide (CAS 38061-70-0)
- 5-Methylisoxazole-3-carboxamide (CAS 3445-52-1)
- 3-Methylisoxazole-5-carboxylic Acid (CAS 4857-42-5)
- 4-Methylisoxazole-3-carboxylic Acid (CAS 215872-46-1)
- 4-Methylisoxazole-5-carboxylic Acid (CAS 261350-46-3)
Recommended Standards
- (Z)-4-(Aminomethylene)-3-methylisoxazol-5(4H)-one (CAS 112548-74-0)
- Pyromeconic Acid O-Methyl Ether (CAS 1193-64-2)
- 1-(5-Methyl-1,3,4-oxadiazol-2-yl)ethanone (CAS 1104197-69-4)
- 2-Methyl-6-hydroxypyrimidin-4-one (CAS 1194-22-5)
- 3-Amino-4,5-dimethylbenzoic acid (CAS 348165-23-1)
- 3-Methyl-5-(3-oxobutyl)-1-benzofuran-2-carboxylic acid (CAS 728898-85-9)
- 4-(3-(2-Cyano-4,5-dimethoxyphenyl)thioureido)-N,N-dimethylbenzenesulfonamide (CAS 692287-56-2)
- 5-Benzyl 7-methyl 8-oxo-5-azaspiro[2.5]octane-5,7-dicarboxylate (CAS 1232542-20-9)
- Anagyrine (CAS 486-89-5)
- Ceftriaxone Impurity 21 (CAS CATO-C4X-116321)
- (S)-1-Cbz-3-Aminopyrrolidine hydrochloride (CAS 550378-39-7)
- 2,2'-((3,5-Bis(decyloxy)phenyl)azanediyl)diacetic acid (CAS 153125-17-8)
- tert-Butyl (S)-1-(3-(benzyloxy)-2-fluoropropyl)-1H-1,2,3-triazole-4-carboxylate (CAS 1853165-96-4)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
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