1-(3,4,5-Trimethoxyphenyl)piperazine hydrochloride CAS 116290-71-2
| CAS No. | 116290-71-2 |
| Molecular Formula | C13H20N2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(3,4,5-Trimethoxyphenyl)piperazine hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(3,4,5-Trimethoxyphenyl)piperazine hydrochloride (CAS 116290-71-2), a certified reference material (molecular formula C13H20N2O3HCl, MW 288.77 g/mol) for analytical method development and quality control.
1-(3,4,5-Trimethoxyphenyl)piperazine hydrochloride (C13H20N2O3HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H20N2O3 HCl |
| Molecular Weight | 288.77 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trimethoxyphenyl Standards
- 3-(3,4,5-Trimethoxyphenyl)propan-1-amine (CAS 100252-79-7)
- 1-(3,4,5-Trimethoxyphenyl)butane-1,3-dione (CAS 100613-36-3)
- 1-(3,4,5-Trimethoxyphenyl)-2-propyn-1-ol (CAS 10079-74-0)
- 3-(3,4,5-Trimethoxyphenyl)pentanedioic acid (CAS 100973-09-9)
- 1016-19-9 3,4,5-Trimethoxyphenyl isocyanate 5-isocyanato-1,2,3-trimethoxybenzene (CAS 1016-19-9)
- 1-(2,4,6-Trimethoxyphenyl)ethan-1-amine (CAS 1020957-63-4)
- (2,3,4-Trimethoxyphenyl)acetone (CAS 102119-67-5)
- 3-(3,4,5-Trimethoxyphenyl)-1H-pyrazol-5-ylamine Hydrochloride (CAS 1025447-52-2)
Recommended Standards
- 1-(5-(tert-Butylthio)-3-methylpyridin-2-yl)-1,2,3,4-tetrahydroquinoline (CAS 1355227-20-1)
- Trihexylphosphine hydrochloride (CAS 1430948-10-9)
- 1-(4-Nitrophenyl)-3-methyl-5-phenylformazan (CAS 68420-26-8)
- N1-(5-Chloro-2-methoxyphenyl)-N2-(2-cyclopropyl-2-hydroxypropyl)oxalamide (CAS 1286720-24-8)
- 5-Fluorobicyclo[3.2.2]Nonan-1-amine (CAS 2091810-58-9)
- Phenoxy-d5-acetic Acid (CAS 154492-74-7)
- N-((Cyclohexylimino)methylene)-N-methylcyclohexanaminium iodide (CAS 36049-77-1)
- 2-([1,2,4]Triazolo[4,3-a]pyridin-3-ylthio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 757203-22-8)
- Baccharin (CAS 61251-97-6)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
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