Methyl 4-formyl-5-methylthiophene-2-carboxylate CAS 116368-68-4

Purity 97%+In StockPharmaceutical Standards
CAS No.116368-68-4
Molecular FormulaC8H8O3S
Molecular Weight184.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 4-formyl-5-methylthiophene-2-carboxylate CAS 116368-68-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 4-formyl-5-methylthiophene-2-carboxylate.

Methyl 4-formyl-5-methylthiophene-2-carboxylate (CAS 116368-68-4), molecular formula C8H8O3S and molecular weight 184.21 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, Methyl 4-formyl-5-methylthiophene-2-carboxylate (C8H8O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 184.21 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Methyl 4-formyl-5-methylthiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H8O3S
Molecular Weight184.21 g/mol
Purity97%+
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Sulfur Atoms1

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