(Z)-3-((hydroxy(methyl)amino)methylene)indolin-2-one CAS 1164473-20-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1164473-20-4
Molecular FormulaC10H10N2O2
Molecular Weight190.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(Z)-3-((hydroxy(methyl)amino)methylene)indolin-2-one CAS 1164473-20-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 190.20 g/mol gives (Z)-3-((hydroxy(methyl)amino)methylene)indolin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(Z)-3-((hydroxy(methyl)amino)methylene)indolin-2-one (CAS 1164473-20-4), molecular formula C10H10N2O2 and molecular weight 190.20 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (Z)-3-((hydroxy(methyl)amino)methylene)indolin-2-one (C10H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (Z)-3-((hydroxy(methyl)amino)methylene)indolin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H10N2O2
Molecular Weight190.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Nitrogen Atoms2

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