3-(benzylsulfonyl)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)acrylamide CAS 1164476-67-8
| CAS No. | 1164476-67-8 |
| Molecular Formula | C16H14Cl2N2O4S |
| Molecular Weight | 401.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 401.26 g/mol gives 3-(benzylsulfonyl)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)acrylamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(benzylsulfonyl)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)acrylamide (CAS 1164476-67-8) is a high-purity analytical reference standard with the molecular formula C16H14Cl2N2O4S and a molecular weight of 401.26 g/mol.
3-(benzylsulfonyl)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)acrylamide (C16H14Cl2N2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(benzylsulfonyl)-2,3-dichloro-N-(6-methoxy-3-pyridinyl)acrylamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14Cl2N2O4S |
| Molecular Weight | 401.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Tert-butyl 4-((5-bromo-3-nitropyridin-2-yl)amino)piperidine-1-carboxylate (CAS 1127119-18-9)
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- 1-(Tert-butyl) 7-methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1,7-dicarboxylate (CAS 1256360-02-7)
- O1-tert-butyl O3-ethyl 5-hydroxyazepane-1,3-dicarboxylate (CAS 2110273-93-1)
- 2-Carbamoylhexanoic acid (CAS 4431-51-0)
- 4-(3-Chlorophenyl)-3-methylbenzoic acid (CAS 1261928-83-9)
- 4,5-Dibenzyl-5-hydroxy Albuterol Acid Methyl Ester (CAS 182676-93-3)
- 5-(Benzyloxy)-1,3-difluoro-2-iodobenzene (CAS 1799824-81-9)
- 4-Methoxy-3-propoxybenzoyl chloride (CAS 144036-21-5)
- 2-(4-(Aminomethyl)bicyclo[2.2.2]octan-1-yl)acetic acid (CAS 802318-11-2)
- (1R,2S)-2-(4-methoxyphenyl)cyclopropan-1-amine hydrochloride (CAS 26568-28-5)
- 5-Ethyl-2-methyl-4,4-diphenyl-3,4-dihydro-2H-pyrrole (CAS 30223-74-6)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
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