(2Z)-2-(2,4-Dichlorophenyl)-3-[2-(methylsulfanyl)quinolin-3-yl]prop-2-enenitrile CAS 1164533-11-2
| CAS No. | 1164533-11-2 |
| Molecular Formula | C19H12Cl2N2S |
| Molecular Weight | 371.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2Z)-2-(2,4-Dichlorophenyl)-3-[2-(methylsulfanyl)quinolin-3-yl]prop-2-enenitrile (CAS 1164533-11-2) is a high-purity analytical reference standard with the molecular formula C19H12Cl2N2S and a molecular weight of 371.28 g/mol.
The molecular framework of (2Z)-2-(2,4-Dichlorophenyl)-3-[2-(methylsulfanyl)quinolin-3-yl]prop-2-enenitrile (C19H12Cl2N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H12Cl2N2S |
| Molecular Weight | 371.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Z Standards
- (2Z)-2-(3,4-Dichlorophenyl)-3-[2-(methylsulfanyl)quinolin-3-yl]prop-2-enenitrile (CAS 1164470-40-9)
- 1-{1-[(3,4-dichlorophenyl)methyl]-4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-3-yl}-1H-pyrrole (CAS 478047-17-5)
- Butyl 4-(3,4-dichlorophenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 5713-78-0)
- N-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydroacridine-9-carboxamide (CAS 853317-91-6)
- 2-((2,5-Dichlorophenyl)amino)-2-oxoethyl 2-(methylthio)nicotinate (CAS 380549-51-9)
- 2-((3,5-Dichlorophenyl)amino)-2-oxoethyl 2-(methylthio)nicotinate (CAS 475055-22-2)
- 4-[(2E)-3-(2,4-Dichlorophenyl)prop-2-enoyl]phenyl methanesulfonate (CAS 331460-77-6)
- 1-(3,4-Dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 872621-61-9)
Recommended Standards
- N,N-Diphenyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 1379789-40-8)
- 106664-95-3 2-Hydroxy-3-[2-(2-hydroxy-3,4-dioxocyclohexa-1,5-dien-1-yl)hydrazinyl]-5-nitrobenzene-1-sulfonic acid DTXSID10552823 (CAS 106664-95-3)
- tert-Butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydro-1,4-epiminonaphthalene-9-carboxylate (CAS 1590387-04-4)
- Tert-butyl 2-((3,5-bis(trifluoromethyl)phenyl)(imino)methyl)hydrazine-1-carboxylate (CAS 1053655-95-0)
- N-(5-((2-(Cyclohexylamino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)pentanamide (CAS 893347-18-7)
- 4,4,5,5-Tetramethyl-2-(2,4,6-trimethoxyphenyl)-1,3,2-dioxaborolane (CAS 269410-04-0)
- Potassium trifluoro(4-((furan-2-ylmethyl)carbamoyl)phenyl)borate (CAS 2017555-09-6)
- Milrinone Impurity 28 (CAS CATO-C4X-109128)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
- 4-(5-(Anthracen-9-yl)-1,3,4-oxadiazol-2-yl)-N,N-dimethylaniline (CAS 70366-91-5)
- 3-[2-(2,5-Dimethyl-1H-pyrrol-1-yl)ethyl]-1H-indole 4284AF 95399-28-3 C16H18N2 (CAS 95399-28-3)
- 1-(2-Bromophenyl)-5-chloro-1-oxopentane (CAS 487058-92-4)
- 3-Iodoimidazo[1,2-a]pyridine-6-carboxylic acid (CAS 1384429-70-2)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
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