1'-Methyl-4'-(p-tolyl)dispiro[chromane-3,3'-pyrrolidine-2',3''-indoline]-2'',4-dione CAS 1164542-34-0
| CAS No. | 1164542-34-0 |
| Molecular Formula | C27H24N2O3 |
| Molecular Weight | 424.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1'-Methyl-4'-(p-tolyl)dispiro[chromane-3,3'-pyrrolidine-2',3''-indoline]-2'',4-dione.
1'-Methyl-4'-(p-tolyl)dispiro[chromane-3,3'-pyrrolidine-2',3''-indoline]-2'',4-dione (CAS 1164542-34-0) is a high-purity analytical reference standard with the molecular formula C27H24N2O3 and a molecular weight of 424.49 g/mol.
The molecular framework of 1'-Methyl-4'-(p-tolyl)dispiro[chromane-3,3'-pyrrolidine-2',3''-indoline]-2'',4-dione (C27H24N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1'-Methyl-4'-(p-tolyl)dispiro[chromane-3,3'-pyrrolidine-2',3''-indoline]-2'',4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H24N2O3 |
| Molecular Weight | 424.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
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