1-(4,5-Dibromothiophene-2-carbonyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine CAS 1164557-05-4
| CAS No. | 1164557-05-4 |
| Molecular Formula | C18H18Br2N2OS |
| Molecular Weight | 470.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(4,5-Dibromothiophene-2-carbonyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine (CAS 1164557-05-4), molecular formula C18H18Br2N2OS and molecular weight 470.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4,5-Dibromothiophene-2-carbonyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine (C18H18Br2N2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(4,5-Dibromothiophene-2-carbonyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18Br2N2OS |
| Molecular Weight | 470.22 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dibromothiophene Standards
- 1-(4,5-Dibromothiophene-2-carbonyl)piperidine-4-carboxamide (CAS 870769-18-9)
- (3,4-Dibromothiophene-2,5-diyl)bis(trimethylsilane) (CAS 175658-90-9)
- 4-(4,5-Dibromothiophene-2-carbonyl)piperazin-2-one (CAS 1090363-55-5)
- 2,5-Dibromothiophene-3-boronic Acid Pinacol Ester (CAS 942070-22-6)
- 3,4-Dibromothiophene-2-sulfonyl chloride (CAS 128852-15-3)
- 2,5-Dibromothiophene-3-sulfonyl chloride (CAS 70374-40-2)
- 4,5-Dibromothiophene-2-sulfonyl chloride (CAS 81606-31-7)
- 2,5-Dibromothiophene-3,4-dicarboxylic Acid (CAS 190723-12-7)
Recommended Standards
- 2-(4-Bromobenzenesulfinyl)-1,1-bis(4-chlorophenyl)ethan-1-ol (CAS 303152-32-1)
- 1,1,2,2-Tetrakis(4-chlorophenyl)ethene (CAS 78525-36-7)
- 1,2-Di[3,5-di(trifluoromethyl)phenyl]diaz-1-en-1-ium-1-olate (CAS 64857-70-1)
- Binimetinib Impurity 2 (CAS CATO-C4X-30502)
- 6-amino-2,3-dihydro-1H-indene-5-sulfonic acid (CAS 36125-91-4)
- (2,4-Difluorophenyl)(3-fluoro-4-methoxyphenyl)methanone (CAS 1154186-23-8)
- propionic acid (CAS 79-09-4)
- Cefprozil Impurity 20 (CAS CATO-C4X-149220)
- 2-(2-chloro-5-hydroxypyridin-4-yl)acetonitrile (CAS 1227576-29-5)
- Rel-(3R,4s,5S)-4-aminoadamantane-1-carboxylic acid (CAS 898265-47-9)
- 1-((3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl)methyl)-3-isopropylquinazoline-2,4(1H,3H)-dione (CAS 1105197-19-0)
- Ethyl 4,4-difluorobut-2-enoate (CAS 1992-97-8)
- 1-(3,4-Dichlorobenzyl)-5-(4-(2-(trifluoromethyl)phenethyl)piperazine-1-carbonyl)pyridin-2(1H)-one (CAS 242472-04-4)
- β-Bag Cell Peptide (Aplysia californica) (CAS 109024-47-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com