Dobutamine Impurity 48 CAS 1165-58-8

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.1165-58-8
Molecular FormulaC24H18
Molecular Weight306.40 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Dobutamine Impurity 48 CAS 1165-58-8 chemical structure

Description

As a certified reference material (CRM), Dobutamine Impurity 48 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

As a process- or degradation-related impurity, Dobutamine Impurity 48 (CAS 1165-58-8, C24H18) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Dobutamine Impurity 48 (C24H18) contains a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC24H18
Molecular Weight306.40 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)16.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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