3-(4-Chlorophenyl)-4-cyano-5-(methylthio)thiophene-2-carboxylic acid CAS 116525-66-7
| CAS No. | 116525-66-7 |
| Molecular Formula | C13H8ClNO2S2 |
| Molecular Weight | 309.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 3-(4-Chlorophenyl)-4-cyano-5-(methylthio)thiophene-2-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 309.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3-(4-Chlorophenyl)-4-cyano-5-(methylthio)thiophene-2-carboxylic acid (CAS 116525-66-7), a certified reference material (molecular formula C13H8ClNO2S2, MW 309.79 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-Chlorophenyl)-4-cyano-5-(methylthio)thiophene-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8ClNO2S2 |
| Molecular Weight | 309.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 1-(5-(4-Chlorophenyl)-2-methyl-1-phenyl-1H-pyrrol-3-yl)ethanone (CAS 100989-43-3)
- 4-(4-Chlorophenyl)-2-(cyclohexylamino)-4-oxobutanoic acid (CAS 1025101-05-6)
- 3-(3-Chlorophenyl)-4-cyano-5-(methylthio)thiophene-2-carboxylic acid (CAS 116493-00-6)
- 4-(3-Chlorophenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine (CAS 1354927-09-5)
- 1-Boc-3-(3'-chlorophenyl)-piperidin-4-one (CAS 869720-07-0)
- 1-Boc-5-(3-chlorophenyl)piperidin-2-one (CAS 2006277-50-3)
- 2-((4-Chlorophenyl)sulfonyl)-3-(2-thienyl)prop-2-enenitrile (CAS 565216-92-4)
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Recommended Standards
- tert-Butyl 2-(4-chlorobenzyl)-4-oxopiperidine-1-carboxylate (CAS 1282523-55-0)
- 2-(2,5-Dimethylphenyl)-3-methylquinoline-4-carbonyl chloride (CAS 1160264-98-1)
- 2-(4-Isopropylphenyl)quinoline-4-carbonyl chloride (CAS 1160264-73-2)
- tert-Butyl (5R,9S)-2-chloro-6,7,8,9-tetrahydro-10H-5,9-methanopyrido[2,3-b][1,4]diazocine-10-carboxylate (CAS 1638603-95-8)
- 4-Hydroxy-2-iodobenzoic acid (CAS 116631-87-9)
- cis-4-(2,5-Dimethylbenzoyl)cyclohexane-1-carboxylic acid (CAS 735270-23-2)
- Methyl 5,7-dichloro-4-hydroxyquinoline-2-carboxylate (CAS 130613-19-3)
- 1,2-Di(naphthalen-2-yl)ethene (CAS 2042-99-1)
- 3-(Pyrazin-2-yloxy)aniline (CAS 633300-16-0)
- 3-Bromopropane-1-sulfonamide (CAS 88496-95-1)
- 6-methyl-3-(methylsulfanyl)-4,5-dihydro-1,2,4-triazin-5-one (CAS 1566-32-1)
- 5-Chloro-3-methylthiophene-2-carbonitrile (CAS 1823351-95-6)
- 5-(3-Phenoxyphenyl)-1H-tetrazole (CAS 374538-02-0)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com