3-Chloro-5-nitroquinoline CAS 116529-79-4
| CAS No. | 116529-79-4 |
| Molecular Formula | C9H5ClN2O2 |
| Molecular Weight | 208.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 208.60 g/mol gives 3-Chloro-5-nitroquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Chloro-5-nitroquinoline (CAS 116529-79-4) is a high-purity analytical reference standard with the molecular formula C9H5ClN2O2 and a molecular weight of 208.60 g/mol.
The molecular framework of 3-Chloro-5-nitroquinoline (C9H5ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-5-nitroquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5ClN2O2 |
| Molecular Weight | 208.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-6-nitroquinoline (CAS 101860-71-3)
- 8-Chloro-1,7-naphthyridine-6-carboxylic acid (CAS 1019111-25-1)
- 3-(4-Chloro-3-nitrophenyl)prop-2-enenitrile (CAS 1027720-44-0)
- 3-Chloro-5-nitroisoquinoline (CAS 10296-47-6)
- 7-Chloro-4-nitroquinoline (CAS 1076199-85-3)
- 6-chloro-3-nitro-pyridine-2-carboxylic acid (CAS 1204400-58-7)
- 8-Chloro-6-nitroquinoline (CAS 121465-04-1)
- 3-Chloro-3-(4-nitrophenyl)prop-2-enenitrile (CAS 126417-79-6)
Recommended Standards
- 2-(Azidomethyl)-5-chloro-1,3-benzoxazole (CAS 1158301-21-3)
- 2-(Azidomethyl)-6-chloro-1,3-benzoxazole (CAS 1158199-79-1)
- 2-(Benzofuran-2-yl)-2-oxoacetyl chloride (CAS 107748-07-2)
- 2-Chloro-5-nitroquinoline (CAS 13067-94-2)
- 2,5-Furandione, polymer with 2-(hydroxymethyl)-2-methyl-1,3-propanediol (CAS 52032-05-0)
- Chroman-5-carbaldehyde (CAS 209256-63-3)
- 6-Chloro-1-(3-fluoro-4-methylphenyl)hexan-1-one (CAS 898761-30-3)
- 4,6,8-Trimethoxyfuro[2,3-b]quinoline (CAS 522-19-0)
- 3-[(3-bromophenyl)methyl]azetidine, trifluoroacetic acid (CAS 2060005-61-8)
- 7-Chloro-8-iodoimidazo[1,2-a]pyridine (CAS 1331823-94-9)
- Ethyl 2-bromo-5-cyano-3-hydroxybenzoate (CAS 1807079-45-3)
- 4,5-Dibromo-3-chlorotoluene (CAS 953794-53-1)
- (R)-2-(3,4-Difluorobenzyl)pyrrolidine-2-carboxylic acid hydrochloride (CAS 1049732-11-7)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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