4-Cyano-5-nitro 1H-Indazole CAS 1167056-44-1
| CAS No. | 1167056-44-1 |
| Molecular Formula | C8H4N4O2 |
| Molecular Weight | 188.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Cyano-5-nitro 1H-Indazole (CAS 1167056-44-1) is a high-purity analytical reference standard with the molecular formula C8H4N4O2 and a molecular weight of 188.14 g/mol.
4-Cyano-5-nitro 1H-Indazole (C8H4N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4N4O2 |
| Molecular Weight | 188.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 4 |
Related Cyano Standards
- 5-Cyano-7H-pyrrolo[2,3-d]pyrimidine-4-carboxylic acid (CAS 1095822-77-7)
- 3-Cyano-6-nitroindazole, 97% (CAS 858661-74-2)
- 4-Cyano-6-fluoroquinoline 1-oxide (CAS 152562-07-7)
- 4-Cyano-5-(difluoromethyl)-3-fluoro-2-hydroxypyridine (CAS 1805084-33-6)
- 4-Cyano-3-(difluoromethyl)-2-fluoro-5-hydroxypyridine (CAS 1806871-11-3)
- 3-Cyano-4-(trifluoromethyl)pyridine 1-oxide (CAS 287922-66-1)
- 3-Cyano-6-cyclopropylpicolinic acid (CAS 1221791-98-5)
- N-(3-Cyano-5-formylphenyl)acetamide (CAS 1393557-35-1)
Recommended Standards
- 2-Oxohexahydropyrimidine-4,6-dicarboxylic acid (CAS 114832-72-3)
- 3-Nitro-1H-pyrrolo[2,3-c]pyridine-7-carbonitrile (CAS 1190314-84-1)
- Benzo[1,2-d:4,5-d']diimidazole-4,8(1H,5H)-dione (CAS 111886-16-9)
- 3-Nitro-1H-pyrrolo[3,2-b]pyridine-7-carbonitrile (CAS 1190316-22-3)
- Dipipanone Hydrochloride-API (CAS 75783-06-1)
- Sodium nonyl sulfate (CAS 1072-15-7)
- N-(1-(Phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)butyramide (CAS 1005301-23-4)
- 8-(Trifluoromethyl)naphthalen-1-ol (CAS 33533-47-0)
- 2-((1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl)terephthalic acid (CAS 302602-92-2)
- Dacomitinib Impurity N4 (CAS 2190490-31-2)
- N-(2,4-Dimethyl-phenyl)-2-(4-ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-acetamide (CAS 924969-62-0)
- 2'-Fluoro-3'-methoxy-[1,1'-biphenyl]-2-carboxylic acid (CAS 1261932-56-2)
- Furo[2,3-h]quinolin-2(1H)-one (CAS 362518-99-8)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com